InsideOut Institute is Australia's national leader in eating disorder research. Our work spans clinical trials, digital innovation, and translation into real-world practice. Through global research partnerships, we are advancing knowledge to improve prevention, early intervention, and treatment for eating disorders, with the ultimate goal of finding a cure.
Engaging lived experience, carers and stakeholders to better understand illness and strategies for support and treatment
The IncludED study is one of Australia's largest investigations into eating and body image concerns within the LGBTQIA+ community, conducted through online surveys with people aged 16+ from across the globe. The findings aim to improve awareness, support, and treatment for eating disorders within these communities, which have been historically under‑researched.
The TailorED study tests innovative interventions for people with Bulimia Nervosa or Binge Eating Disorder who don't respond well to standard cognitive behavioural therapy, comparing personalised care with brain stimulation (TMS). This stepped-care approach aims to optimise treatment outcomes, reduce costs and waiting times, and provide evidence for tailoring care based on individual treatment response.
This trial will develop and evaluate a personalised package of care for young people with anorexia nervosa aged 14-25 through co-production with individuals and families, with treatment tailored based on regular clinical and psychometric review.
This study applies nutritional geometry to food diary records from 200 people with Binge Eating Disorder or Bulimia Nervosa to investigate whether insufficient protein intake drives overconsumption and loss of dietary control.
EDGI is a world-first genome-wide association study conducted in collaboration with QIMR Berghofer and international researchers. It aims to identify the hundreds of genes contributing to Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, and ARFID, to enable more targeted, personalised interventions and earlier detection in high-risk groups.
This project develops a data-driven model of treatment personalisation using pre-existing clinical datasets to identify individual-level intervention targets for eating disorders, followed by a pilot study assessing preliminary efficacy, acceptability, and feasibility.
The My Diet Study is the first longitudinal, observational investigation of self-directed dieting patterns in young people aged 16-25, combining in-depth psychological and biological data to understand factors impacting dieting experiences. By examining natural dieting habits before eating disorders emerge, the research aims to identify biomarkers for risk, inform safety frameworks for young people's dieting, and establish evidence-based guidance for diet-based lifestyle interventions.
This trial evaluates the safety, feasibility, and preliminary efficacy of psilocybin-assisted psychotherapy for individuals with treatment-resistant anorexia nervosa who have not responded to standard evidence-based interventions.
This study investigates brain and hormonal responses to real-time food consumption decisions in individuals with anorexia nervosa using brain imaging and biomarker analysis. The research aims to identify biological drivers of restrictive eating and inform development of novel treatment targets.
The livED project offers a digital platform for people to share their experiences of living with and getting treatment for body image, eating or exercise concerns. The project aims to improve and diversify our understanding of eating disorders within the community and to inform health system approaches.
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InsideOut acknowledges the tradition of custodianship and law of the Country on which the University of Sydney and Charles Perkins Centre campus stands. We pay our respects to those who have cared and continue to care for Country. We are committed to diversifying research and eliminating inequities and discrimination in healthcare. We welcome all people regardless of age, gender, race, size, sexuality, language, socioeconomic status, location or ability.