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Kristi Griffiths

Kristi Griffiths

(she/her)

Acting Research Stream Lead & Senior Research Fellow

research

About

Kristi completed her PhD in behavioural neuroscience at the University of Sydney. She was subsequently awarded a Tenix Foundation Postdoctoral Fellowship, followed by a NHMRC Early Career Fellowship. She completed neuroimaging training with the fMRI Visiting Fellowship at the Martinos Center for Biomedical Imaging in Boston.

Kristi has published more than 50 peer-reviewed papers, which have been highly cited (1000+), and she has secured >1.3 million dollars in competitive research funding. She is a peer reviewer for top international journals and has served as a reviewer for international grant funding bodies (e.g. Agency for Health Quality and Assessment of Catalonia).

Kristi's research program applies multimodal neuroimaging techniques to better understand mechanisms of psychiatric illnesses and how they are affected by pharmacotherapies, with the ultimate goal of advancing personalised medicine.

Kristi is available for HDR and PhD Supervision.

Projects

research

Holistic Understanding: Deeply phenotyping eating disorders

The Holistic Understanding study is a longitudinal, biopsychosocial dense-sampling study designed to uncover the mechanisms underlying eating disorder development and maintenance, addressing gaps in current understanding that limit treatment efficacy.

livedExperience

A community survey of Ozempic and GLP-1 agonist use

This study examines who is using GLP-1 agonists (Ozempic, Wegovy, Mounjaro) and their experiences, particularly regarding physical and mental health outcomes, side effects, and associations with disordered eating. Through surveys and interviews with users aged 18+, the research aims to identify the benefits and harms of these medications and provide insights into their real-world effects on health and wellbeing.

livedExperience

FERN Study: How do the brain and hormones influence calorie intake in people with Anorexia Nervosa?

This study investigates brain and hormonal responses to real-time food consumption decisions in individuals with anorexia nervosa using brain imaging and biomarker analysis. The research aims to identify biological drivers of restrictive eating and inform development of novel treatment targets.

clinical

Panorexia: A clinical trial of psilocybin-assisted psychotherapy for treatment-resistant Anorexia Nervosa

This trial evaluates the safety, feasibility, and preliminary efficacy of psilocybin-assisted psychotherapy for individuals with treatment-resistant anorexia nervosa who have not responded to standard evidence-based interventions.

livedExperience

My Diet Study: Exploring initial eating disorder risk among adolescent and young adult dieters in the community

The My Diet Study is the first longitudinal, observational investigation of self-directed dieting patterns in young people aged 16-25, combining in-depth psychological and biological data to understand factors impacting dieting experiences. By examining natural dieting habits before eating disorders emerge, the research aims to identify biomarkers for risk, inform safety frameworks for young people's dieting, and establish evidence-based guidance for diet-based lifestyle interventions.

Selected Publications

Exploring Bi-Directional Impacts of Lisdexamfetamine Dimesylate on Psychological Comorbidities and Quality of Life in People with Binge Eating Disorder

Griffiths, K. R., Boulet, S., Barakat, S., Touyz, S., Hay, P., Maguire, S., & Kohn, M. R.

Journal of Eating Disorders.

12(1), 80.

View Article

Functional Connectivity Mechanisms Underlying Symptom Reduction Following Lisdexamfetamine Treatment In Binge Eating Disorder: A Clinical Trial

Griffiths, K., Breukelaar, I., Harvie, G., Yang, J., Foster, S., Harris, A., Clarke, S., Hay, P., Touyz, S., Korgaonkar, M., Kohn, M.

Biological Psychiatry: Global Open Science.

4(1), 317 - 325.

View Article

White Matter Microstructural Differences in Underweight Adolescents with Anorexia Nervosa and a Preliminary Longitudinal Investigation of Change Following Short-Term Weight Restoration

Griffiths, K., Martin Monzon, B., Madden, S., Kohn, M., Touyz, S., Sachdev, P., Clarke, S., Foroughi, N., Hay, P.

Eating and Weight Disorders.

26(6), 1903 - 1914.

View Article

Task-Evoked Effective Connectivity in Salience and Central Executive Networks Predicts Cognitive Control Ability and Inattention Symptoms in Children With ADHD.

Cai, W., Griffiths, K., Korgaonkar, M., Williams, L., Menon, V.

Biological Psychiatry.

85(10).

View Article

Impulsivity and Its Relationship With Lisdexamfetamine Dimesylate Treatment in Binge Eating Disorder

Griffiths, K. R., Aparício, L., Braund, T. A., Yang, J., Harvie, G., Harris, A., ... & Kohn, M. R.

Frontiers in Psychology.

12.

View Article

Interest Areas

neurobiological

digital-mental-health

understanding-illness-lived-experience

treatment-innovation

Qualifications

PhD in Behavioural Neuroscience, University of Sydney

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